2025. Hegazy, N; … (many co-authors – WSI Consortium). Variability of Clinical Metrics in Small Population Communities Drive Perceived Wastewater and Environmental Surveillance Data Quality: Ontario, Canada-Wide Study. ACS ES&T Water Article ASAP. DOI: 10.1021/acsestwater.4c00958
2025. Elliott, CI; Simmons, DBD; Stotesbury, T. Integrating time since deposition estimation of bloodstains into a DNA profiling workflow: A novel approach using fluorescence spectroscopy. Talanta, Volume 284.
2024. Mateus, M; Hammill, ML; Simmons, D; Desaulniers, J-P. Injection of ortho-functionalized tetrafluorinated azobenzene-containing siRNAs into Japanese medaka embryos for photocontrolled gene silencing. Current Protocols, 4, e70051.
2024. D’Aoust, PM; Hegazy, N; Ramsay, NT; et al. SARS-CoV-2 viral titer measurements in Ontario, Canada wastewaters throughout the COVID-19 pandemic. Sci Data 11, 656.
2024. Mateus, M; Hammill, ML; Simmons, DBD; and Desaulniers, J-P. In Vivo Injection of Reversible Optically Controlled Short Interfering RNA into Japanese Medaka Embryos (Oryzias latipes) to Regulate Gene Silencing. ACS Chemical Biology 19 (9), 1904-1909.
2024. Pollard, S; De Silva, AO; Simmons†, DBD. Metabolic, neurotoxic, and immunotoxic effects of PFAAs and their mixtures on the proteome of the head kidney and plasma from rainbow trout (Oncorhynchus mykiss). Science of The Total Environment. 928: 172389.
2024. Ivantsova, E; Henry, EE; Konig, I; English, CD; Souders, CL; Point, AD; Simmons, DBD; Martyniuk, CJ. Waterborne exposure to the antineoplastic 5-fluorouracil alters lipid composition in larval zebrafish (Danio rerio). Science of The Total Environment. 928: 172377.
2024. Islam, G; Gedge, A; Ibrahim, R; de Melo, T; Lara-Jacobo, L; Dlugosz, T; Kirkwood, AE; Simmons, D; Desaulniers, JP. The role of catchment population size, data normalization, and chronology of public health interventions on wastewater-based COVID-19 viral trends. Science of The Total Environment. 937: 173272.
2024. Oliveira Pereira, E; Warriner, T; Simmons, D; Jobst, K; Simpson, A; Simpson, M. Metabolomic-Based Comparison of Daphnia magna and Japanese Medaka Responses with Exposure to Acetaminophen, Diclofenac, and Ibuprofen. Environ Toxicol Chem. 43 (6): 1339–1351.
2024. De Melo, T; Islam, G; Simmons, DBD; Desaulniers, JP; Kirkwood, AE. An alternative method for monitoring and interpreting influenza A in communities using wastewater surveillance. Frontiers in Public Health 11, 1141136.
2023. Tannouri, N and Simmons, DBD. Characterizing the origin of blood plasma proteins from organ tissues in rainbow trout (Oncorhynchus mykiss) using a comparative non-targeted proteomics approach. Comparative Biochemistry and Physiology – Part D: Genomics and Proteomics. 46: 101070.
2023. McNabney, DWG: Mangal, V; Kirkwood, AE; Simmons, DBD. Phytoplankton metabolite profiles from two Lake Ontario Areas of Concern reveal differences associated with taxonomic community composition. Science of the Total Environment. 871: 162042
2023. Ivantsova, E; Konig, I; Souders, CL; McNabney, DWG; Simmons, DBD; Martyniuk. CJ. Lipidomic, metabolomic, and behavior responses of zebrafish (Danio rerio) exposed to environmental levels of the beta blocker atenolol. Science of the Total Environment. 866: 161272.
2022. Simmons, DBD and Palace, V. Editorial: Non-lethal approaches in environmental science. Frontiers in Genetics. doi: 10.3389/fgene.2022.1086605.
2022. Martyniuk, CJ and Simmons, DBD. Sex-specific omic responses in animal physiology and toxicology. Comp Biochem Physiol Part D Genomics Proteomics. 42:100990. doi: 10.1016/j.cbd.2022.100990.
2022. Pollard, S; Anderson, JC; Bah, F; Mateus, M; Sidhu, M; Simmons. DBD. Non-Lethal Blood Sampling 5f Fish in the lab and Field with Methods for Dried Blood Plasma Spot Omic Analyses. Frontiers in Genetics. Vol. 13. DOI: 10.3389/fgene.2022.795348.
2022. Wagner, ND; Simmons, DBD; Prater, C; Frost, PC. Proteome changes in an aquatic invertebrate consumer in response to different nutritional stressors. Oecologia. 199:329-341.
2022. Eric Arts, Stephen Brown, David Bulir, Trevor C Charles, Christopher T DeGroot, Robert Delatolla, Jean-Paul Desaulniers, Elizabeth A Edwards, Meghan Fuzzen, Kimberley Gilbride, Jodi Gilchrist, Lawrence Goodridge, Tyson E Graber, Marc Habash, Peter Jüni, Andrea Kirkwood, James Knockleby, Christopher Kyle, Chrystal Landgraff, Chand Mangat, Douglas G Manuel, R Michael McKay, Edgard Mejia, Aleksandra Mloszewska, Banu Ormeci, Claire Oswald, Sarah Jane Payne, Hui Peng, Shelley Peterson, Art FY Poon, Mark R Servos, Denina Simmons, Jianxian Sun, Minqing Yang, Gustavo Ybazeta. Community Surveillance of Omicron in Ontario: Wastewater-based Epidemiology Comes of Age. Pre-print, Research Square: 10.21203/rs.3.rs-1439969/v2
2022. Lara-Jacobo, L, Islam, G, Desaulniers, J-P, Kirkwood, A, Simmons, DBD. Detection of SARS-CoV-2 Proteins in Wastewater Samples by Mass Spectrometry. Environmental Science and Technology. 56(8):5062-5070.
2021. G Islam, A Gedge, L Lara-Jacobo, A Kirkwood, D Simmons, JP Desaulniers. Pasteurization, storage conditions and viral concentration methods influence RT-qPCR detection of SARS-CoV-2 RNA in wastewater. Science of The Total Environment, 153228.
2021. Shahmohamadloo, RS, Ortiz, XA, Simmons, DBD, Bhavsar, SP, Watson-Leung, T, and Sibley, PK. Fish tissue accumulation and proteomic response to cyanobacterial toxins is species-dependent. Chemosphere. ID: CHEM85588
2021. Leger, JAD; Athanasio, CG; Zhera, A; Chauhan, MF; Simmons, DBD. Hypoxic responses in Oncorhynchus mykiss involve angiogenesis, lipid, and lactate metabolism, which may be triggered by the cortisol stress response and epigenetic methylation. Comparative Biochemistry and Physiology – Part D: Genomics and Proteomics. 39: 100860.
2021. Shahmohamadloo, RS; Ortiz, XA; Simmons, DBD; Lumsden, JS; Bhavsar, SP; Watson-Leung, T; Eyken, AV; Hankins, G; Hubbs, K; Konopelko, P. Sarnacki; M, Strong, D; and Sibley, PK. Cyanotoxins within and Outside of Microcystis aeruginosa Cause Adverse Effects in Rainbow Trout (Oncorhynchus mykiss). Environmental Science & Technology. 55(15): 10422–10431
2021. Schreckenbach, Sophia A; Simmons, Denina; Ladak, Adam; Mullin, Lauren; Muir, Derek CG; Simpson, Myrna J; Jobst, Karl J. Data-Independent Identification of Suspected Organic Pollutants Using Gas Chromatography–Atmospheric Pressure Chemical Ionization–Mass Spectrometry. Analytical Chemistry.
2021. Ortega, VA; Boyle, D; Hodgkinson, JW; Simmons, DBD; Belosevic, M; Stafford, JL; Goss, GG. Polymer-coated TiO2 nanoparticles bioaccumulate, immunoactivate and suppress pathogenic Mycobacterium chelonae clearance when intravenously injected into goldfish (Carassius auratus L.).Environmental Science: Nano. 8: 1920-1926.
2021. Liang, X; Martyniuk, CJ; Simmons, DBD. Current topics in omics, ecotoxicology, and environmental science. Comparative Biochemistry and Physiology Part D: Genomics and Proteomics. 38: 100782.
2021. Ussery, E; Bridges, KN; Simmons, DBD; Pandelides, Z; Mansfield, C; Holdway, D. An ‘omics approach to investigate the growth effects of environmentally relevant concentrations of guanylurea exposure on Japanese medaka (Oryzias latipes). Aquatic Toxicology. 232: 105761.
2020. Liang, Xuefang; Martyniuk, Christopher J; Simmons, Denina BD. Are we forgetting the “proteomics” in multi-omics ecotoxicology? Comparative Biochemistry and Physiology Part D: Genomics and Proteomics, 100751.
2020. Pinheiro, MDO; Simmons, DBD; Villella, M; Tetreault, GR; Muir, DCG; McMaster, ME; Hewitt, LM; Parrott, JL; Park, BJ; Brown, SB. Brown bullhead at the St. Lawrence River (Cornwall) Area of Concern: health and endocrine status in the context of tissue concentrations of PCBs and mercury. Environmental Monitoring and Assessment, 192: 1-23.
2020. Michael Moreton; Bonnie Lo; Dennina Simmons; Vicki Marlatt. Toxicity of the aquatic herbicide reward®, on the fathead minnow with pulsed-exposure proteomic profile. Comparative Biochemistry and Physiology Part D: Genomics and proteomics, 33: 100635.
2020. René Shahmohamadloo; Denina Simmons; Paul Sibley. Shotgun proteomics analysis reveals sub-lethal effects in Daphnia magna exposed to cell-bound microcystins produced by Microcystis aeruginosa. Comparative Biochemistry and Physiology Part D: Genomics and proteomics, 33: 100656.
2019. Denina Simmons; Andrew Cowie; Jin Koh; James Sherry; Christopher Martyniuk. Hepatic proteome network data in zebrafish (Danio Rerio) liver following dieldrin exposure. Data in brief, 25: 104351.
2019. Denina Simmons; Andrew Cowie; Jin Koh; James Sherry; Christopher Martyniuk. Label-free and iTRAQ proteomics analysis in the liver of zebrafish (Danio rerio) following dietary exposure to the organochlorine pesticide dieldrin. Journal of Proteomics, 202: 103362.
2017. Xuefang Liang; April Feswick; Denina Simmons; Chris Martyniuk. Environmental toxicology and omics: a question of sex. Journal of Proteomics, 172: 152-164. (Invited submission).
2017. Simmons D, McCallum E, Balshine S, Chandramouli B, Cosgrove J, Sherry J. Reduced anxiety is associated with the accumulation of six serotonin reuptake inhibitors in wastewater treatment effluent exposed, goldfish Carassius auratus. Scientific Reports 7, Article number: 17001.
2017. Simmons D, Miller J, Clarence S, McCallum E, Balshine S, Chandramouli B, Cosgrove J, Sherry J. Altered expression of metabolites and proteins in wild and caged fish exposed to wastewater effluents in an urban wetland. Scientific Reports 7, Article number: 17000.
2017. Derek Muir, Denina Simmons, Xiaowa Wang, Tom Peart, Maria Villella, Jason Miller and Jim Sherry. Bioaccumulation of pharmaceuticals and personal care product chemicals in fish exposed to wastewater effluent in an urban wetland. Scientific Reports 7, Article number: 16999.
2016. João L. C. Ribas, James P. Sherry, Aleksander R. Zampronio, Helena C. Silva de Assis, Denina B.D. Simmons. Inhibition of immune responses and related proteins in Rhamdia quelen exposed to Diclofenac.Environmental Toxicology and Chemistry, 36: 2092–2107.
2016. Christopher J. Martyniuk and Denina B.D. Simmons. Spotlight on Environmental Omics and Toxicology: A long way in a short time. Comparative Biochemistry and Physiology – Part D: Genomics and Proteomics, 19: 97–101. Special Issue: Environmental Omics & Toxicology.
2016. Denina B.D. Simmons and James P. Sherry. Plasma proteome profiles of white sucker (Catostomus commersonii) from the Athabasca River within the Oil Sands deposit demonstrate site-specific differences in biological function. Comparative Biochemistry and Physiology – Part D: Genomics and Proteomics, 19: 181–189. Special Issue: Environmental Omics & Toxicology.
2015. Simmons, D.B.D., Benskin, J., Cosgrove J., Dunker, B., Eckman, D., Martynuik, C.M., Sherry, J. Omics for aquatic ecotoxicology: Control of extraneous variability to enhance the analysis of environmental effects. Environmental Toxicology and Chemistry; 34(8): 1693–1704.
2015. Victoria Tkatcheva, David Poirier, Richard Chong-Kit, Vasile I. Furdui, Christopher Burr, Ray Leger, Jaspal Parmar, Teresa Switzer, Stefanie Maedler, Eric J. Reiner, James P. Sherry, and Denina B.D. Simmons. Lithium disrupts homeostasis in short-term exposure of rainbow trout. Aquatic Toxicology; 161:85-93.
2014. Simmons, D.B.D. , M.E. McMaster, E.J. Reiner, L.M. Hewitt, J.L. Parrott, B.J. Park, S.B. Brown, and J.P. Sherry. Wild fish from the Bay of Quinte Area of Concern contain elevated tissue concentrations of PCBs and exhibit evidence of endocrine-related health effects. Environment International, 66:124-137.
2013. Helena C. Silva de Assis, Jake M. Zamora, Wudu E. Lado, Ahmed M. Al-Ansari, Denina Simmons, James P. Sherry, Jules M. Blais, Vance L. Trudeau. Estrogen-like effects in male goldfish co-exposed to fluoxetine and 17 alpha-ethinylestradiol. Environmental Science & Technology, 47(10): 4961-5516. Cover story.
2012. Simmons, D.B.D., Bols, N.C., Duncker, B.P., McMaster, M., Miller, J.A., Sherry, J.P. Proteomic profiles of white sucker (Catostomus commersonii) sampled from within the Thunder Bay Area of Concern reveal up-regulation of proteins associated with tumor formation and exposure to environmental estrogens. Environmental Science & Technology, 46(3):1886-1894.
EDITED PUBLICATIONS
2016. Chris Martyniuk and Denina Simmons (guest editors). Comparative Biochemistry and Physiology – Part D: Genomics and Proteomics, Volume 19. Special Issue: Environmental Omics & Toxicology.
